Therapist Unlimited Blog

PREGNANT women if possible should avoid taking anti-epilepsy drugs since doing so could affect the intelligence quotient of their unborn child.
Recent research at the University of Liverpool suggest that children aged three years and younger, who are born to women taking the anti-epileptic drug sodium valproate whilst pregnant, are likely to have an IQ of six to nine points lower than average.
The study looks into 300 three-year-olds in the UK and US, whose mothers took one of four anti-epilepsy drugs (AEDs) while pregnant.
According to the initial findings those children exposed to the drug sodium valproate had lower IQ results than children exposed to other AEDs, regardless of the mother’s IQ.
The researchers also took dosage, duration of pregnancy and mother’s consumption of folic acid while pregnant.

A recent study has shown that an anti-epilepsy drug has harmful effects on IQ of unborn children.

Gus Baker, professor of Clinical Neuropsychology at the University of Liverpool explained their research looked at how exposure to sodium valproate and other AEDs in the womb affected children’s everyday life in particular their IQ, memory and language
abilities from one to six years of age.
Based on studies, some 5,000 women with epilepsy become pregnant every year in the UK and the majority of these, including those on AEDs, will experience uncomplicated pregnancies and births.
Earlier studies on the matter has already shown that children exposed to AEDs such as sodium valproate in the womb are more likely to suffer birth defects characterized by
heart malformations, dysmorphic features and minor limb deformities.
Baker said the answer is not as simple as to take women off AEDs altogether as the effects of suffering a seizure can also pose a risk for both mother and unborn child.
He said it is vital that the research is now used to educate women with epilepsy before they start to plan for a family.
Furthermore, Baker said women need to be aware of the risks so that they can make informed choices with the help and advice of experts.
Baker said it is also important that women do not stop taking AED treatment without taking advice from their medical practitioner.
He said it is important to stress that sodium valproate is used globally and it has a favorable safety profile for all adult patients who use it.
He added it has a range of pharmaceutical uses including bipolar disorder, migraine, epilepsy, and in adults sodium valproate is extremely effective.