Therapist Unlimited Blog

Those persons seeking to use aspirin as prevention against cardiovascular disease better abandon the plan now.
A recent medical research has uncovered that the use of low-dose aspirin to ward off heart attacks and strokes in those yet to develop obvious cardiovascular disease can cause serious medical complications.
In the medical world, low-dose aspirin is widely used to prevent further episodes of cardiovascular disease in people who have already had problems such as a heart attack or stroke.
This method known as secondary prevention is well established and of confirmed benefit.
But it is the use of aspirin in primary prevention for those without symptoms, who have not yet had, for example, a heart attack or stroke, but who may be at risk of doing so, following an analysis of the available evidence.
In 2000, cardiovascular disease accounted for two million deaths across the European Union alone, and "worldwide, many people take aspirin every day in the belief that doing so helps prevent cardiovascular disease," says the researchers.

Aspirin could be fatal if not used properly.

The researchers points to various guidelines issued between 2005 and 2008 that recommend aspirin for the primary prevention of cardiovascular disease in various groups of patients. Examples include people aged 50 and older with type 2 diabetes and those with high blood pressure.
But the team explained that the current evidence does not back up the routine use of low-dose aspirin in such groups, because of the potential risk of serious gastrointestinal bleeds that accompany its use and the negligible impact it has on curbing death rates.
Doctors should review all patients currently taking low-dose aspirin for primary prevention, either as prescribed or over-the-counter treatment, says the research team.
"And the decision about whether to continue or stop treatment should be made only after fully informing patients of the available evidence", they added.
"Furthermore,  the researchers concluded that current evidence for primary prevention suggests the benefits and harms of aspirin in this setting may be more finely balanced than previously thought, even in individuals estimated to be at high risk of experiencing cardiovascular events, including those with diabetes or elevated blood pressure.
The researchers believe, that low dose aspirin prophylaxis should not be routinely used for primary prevention.

Proper design  is everything to make sure children are safe from harm.
Keeping children safe from injuries is a must since injury is the leading cause of death for children over the age of 1 in industrialized countries and improving the safety of the man made (built) environment will benefit children’s health.
Based on the recent study,injury accounts for about 40% of childhood deaths in industrialized countries and is even higher in developing countries.
It often involves failure to negotiate a manmade environment. Death rates from injury in affluent countries is 15.3 per 100,000 boys and 10 per 100,000 for girls among children 14 and younger. In developing countries, the rates are 50.5 per 100,000 boys and 43.5 per 100,000 girls.
In 2002, 371,000 boys and 289,000 girls worldwide died of injury, with more than 180,000 mostly pedestrians killed by traffic.
In addition to causing injury and death, unsafe environments are barriers to physical activity that is important to life long health. Changes such as speed control, traffic light phasing, fencing spaces and enhancing pedestrian visibility can reduce injuries by 50 to 75% in specific locations and 25% in wider areas. By making traffic safer for children, it increases the likelihood they will walk to school and can derive health benefits from physical activity.
In fact, 50% of Canadian children never walk to school compared with only 17% who do most of the time.
"By giving priority to automotive over pedestrian transportation we have allowed road traffic to become the leading cause of death among our children,"
 writes Dr. Andrew Howard of the University of Toronto and The Hospital for Sick Children (SickKids). "North American children are increasingly sedentary," and urban sprawl is linked to higher rates of traffic injury and obesity.

Keep your children safe from harm by making their environment free from danger through proper design.

Other ways to modify the built environment include appropriate playground equipment that minimizes injuries while encouraging activity. Falls from climbing
equipment are 5 times more likely to result in severe fractures than falls from a standing height. Evidence shows that playgrounds that did not comply with standards from the Canadian Standards Association (CSA) had twice the rate of injury of compliant playgrounds, although these standards are voluntary without regulatory authority for most Canadian playgrounds.
Fencing around pools to limit deaths from drowning and modification of homes and apartments to prevent falls from windows are other examples of changes to physical surroundings that can save children’s lives.
"Our built environment influences our children’s levels of activity, their physical health and their risk for injury," writes Dr. Howard. "Intelligent planning, particularly with consideration for urban design and traffic engineering to emphasize safe walking and cycling, has enormous potential to improve the health and safety of children now and across the lifespan."

Who says drinking too much coffee is bad for the health?
A recent medical study has shown that patients with chronic hepatitis C and advanced liver disease who drink three or more cups of coffee per day have a 53% lower risk of liver disease progression than non-coffee drinkers.
Based on the research made by Neal Freedman, Ph.D., MPH, from the National Cancer Institute (NCI) it was discovered that that patients with hepatitis C-related bridging fibrosis or cirrhosis who did not respond to standard disease treatment benefited from increased coffee intake.
Freedman explained an effect on liver disease was not observed in patients who drank black or green tea.
It is said that hepatitis C virus (HCV) infects approximately 2.2% of the world’s population with more than 3 million Americans infected. The Centers for Disease Control and Prevention (CDC) cites HCV as the leading cause of liver transplantation in the U.S. and accounts for 8,000 to 10,000 deaths in the country annually. Globally, the World Health Organization (WHO) estimates 3 to 4 million persons contract HCV each year with 70% becoming chronic cases that can lead to cirrhosis of the liver and liver cancer.
This study included 766 participants enrolled in the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (HALT-C) trial who had hepatitis C-related bridging fibrosis or cirrhosis and failed to respond to standard treatment of the anti-viral drugs peginterferon and ribavirin.

It is time to drink coffee for chronic hepatitis C patients.

At the onset of the study, HALT-C patients were asked to report their typical frequency of coffee intake and portion size over the past year, using 9 frequency categories ranging from ‘never’ to ‘every day’ and 4 categories of portion size (1 cup, 2 cups, 3-4 cups, and 5+ cups). A similar question was asked for black and green tea intake. "This study is the first to address the association between liver disease progression related to hepatitis C and coffee intake," stated Freedman.
Participants were seen every 3 months during the 3.8-year study period to assess clinical outcomes which included: ascites (abnormal accumulation of fluid in the abdomen), prognosis of chronic liver disease, death related to liver disease, hepatic encephalopathy (brain and nervous system damage), hepatocellular carcinoma (liver cancer), spontaneous bacterial peritonitis, variceal hemorrhage, or increase in fibrosis. Liver biopsies were also taken at 1.5 and 3.5 five years to determine the progression of liver disease.
Results showed that participants who drank 3 or more cups of coffee per day had a relative risk of .47 for reaching one of the clinical outcomes. Researchers did not observe any association between tea intake and liver disease progression, though tea consumption was low in the study. "Given the large number of people affected by HCV it is important to identify modifiable risk factors associated with the progression of liver disease," said Freedman. "Although we cannot rule out a possible role for other factors that go along with drinking coffee, results from our study suggest that patients with high coffee intake had a lower risk of disease progression."

According to a recent study one of the best steps to have a good result on examination day is to eat the rights foods.
The experts explained having a balance diet promote better concentration for the one taking the examination.
The experts revealed eating energy bars, lollies and chocolates will only give short-term energy for students which is not that beneficial for them during examination day.
 

To have great result during examination students need to eat well for them to have a long lasting energy to answer all the questions correctly.
Here are other practical steps students could use to have a great result while taking their examination.

A. Breakfast that rocks
 

Eat traditional breakfast foods that has carbohydrates, vitamins and minerals.
Try:
- A bowl of cereal with reduced-fat milk, topped with chopped fruit and a sprinkle of almonds
- Wholegrain or wholemeal toast with reduced-fat cheese and tomato, and a small fruit juice.
 

B. Eat regularly throughout the day - Eating energy-sustaining foods at meals and snacks will help to fuel the brain, maintain energy levels, and avoid dips in concentration.

Try:
- Sandwich, roll or wrap filled with salad vegetables, reduced-fat cheese, lean meat or tinned tuna
- Fruit smoothies made with reduced-fat milk and/or yoghurt
- Fruit (fresh, tinned or dried) or fruit and nut snack packs
- Crackers with tomato and reduced-fat cheese, toast and spreads, fruit bread, cereal with reduced-fat milk.

C. Drink plenty of water– This will hydrate your body, help reduce fatigue and help your brain work. If possible, take a water bottle in to the exam with you.

D. Limit excess caffeine— Limit coffee, caffeinated soft drinks or guarana-containing drinks. Caffeine can act as a mild stimulant, boosting alertness and staving off fatigue, but too much can make you feel nervous and restless, and may affect how well you sleep.

E. Exercise - Schedule in some physical activity before or in between exams. Exercise can help reduce stress, clear your mind and improve sleep patterns.

Those persons suffering from rhinosinusitis has a high tendency to also suffer from depression due to their medical condition.
This was the result of a new study conducted on 73 patients wherein some 9.6 percent of these people suffered depression due to their condition.
The research also showed that 20.5 percent scored in the range of a major depressive disorder using an objective screening instrument with high sensitivity and specificity for diagnosing depression, the Patient Health Questionnaire-9.
Additionally, the disease-specific and general health-related quality of life (QOL) in these patients was worse than those who did not exhibit signs of depression.

Patients inflicted with rhinosinusitis better be careful since their medical condition could also result in depression.

Patients with depression and CRS scored significantly worse in most QOL measures, including bodily pain, and physical and social functioning. The authors believe this casts particular light on the impact of depression on diseases of the head and neck, which is to this point little is understood.
They contend that if physicians are to optimize their patients’ health, screening for both CRS and depression is warranted.

Patients suffering from diabetes had reasons to be happy these days.
A recent medical study has shown that grapes had some substance that could help prevent and cure diabetes.
According to the research, a naturally produced molecule called resveratrol, found in the skin of red grapes, has been shown to lower insulin levels in mice when injected directly into the brain, even when the animals ate a high-fat diet.
The study s from a new UT Southwestern Medical Center study suggest that when acting directly on certain proteins in the brain, resveratrol may offer some protection against diabetes. Prior research has shown that the compound exerts anti-diabetic actions when given orally to animals with type 2 diabetes (non-insulin dependent diabetes mellitus), but it has been unclear which tissues in the body mediated these effects.
Dr. Roberto Coppari, assistant professor of internal medicine at UT Southwestern explained their research shows that the brain plays an important role in mediating resveratrol’s anti-diabetic actions, and it does so independent of changes in food intake and body weight.
Coppari added these animals were overrun with fat and many of their organs were inflamed.
He said  when we delivered resveratrol in the brain, it alleviated inflammation in the brain.
He revealed the main reason is that resveratrol does not cross the blood brain barrier efficiently.
"In order for the brain to accumulate the same dose of resveratrol delivered in our study, the amounts of red wine needed daily would surely cause deleterious effects,especially in the liver," Coppari said.
Coppari said their study points out that resveratrol’s analogs that selectively target the brain may help in the fight against diet-induced diabetes."

A latest medical study has shown that grapes could help prevent and cure diabetes.
 

For the study, the researchers investigated what happens when resveratrol acts only in the brain. Specifically, they wanted to know whether resveratrol injected in the brain activated a group of proteins called sirtuins, which are found throughout the body and thought to underlie many of the beneficial effects of calorie restriction. Previous animal research has shown that when these proteins are activated by resveratrol, diabetes is improved. In addition, drugs activating sirtuins currently are being tested as anti-diabetic medications in human trials, Coppari said.
In one group of animals, researchers injected resveratrol directly into the brain; another group received a saline-based placebo. All the surgically treated animals consumed a high-fat diet before and after the surgery.
Coppari said the insulin levels of the animals treated with the placebo solution rose increasingly higher post-surgery. "That’s a normal outcome because insulin sensitivity decreases the longer you keep an animal on a high-fat diet."
Insulin levels in the mice given resveratrol, however, actually started to drop and were halfway to normal by the end of the five-week study period, even though the animals remained on a high-fat diet.
In addition, the researchers found that resveratrol did indeed activate sirtuin proteins in the brain.
Coppari said the findings support his team’s theory that the brain plays a vital role in mediating the beneficial effects of resveratrol and that manipulation of brain sirtuins also may have other beneficial outcomes. "By knowing that the central nervous system is
involved, pharmaceutical companies can begin to focus on developing drugs that selectively target sirtuins in the brain," he said.
The next step, Coppari said, is to determine precisely which neurons in the brain are mediating the effects of the resveratrol.
Other UT Southwestern researchers involved in the study include Drs. Giorgio Ramadori, Laurent Gautron and Teppei Fujikawa, postdoctoral researchers in internal medicine; Dr. Claudia Vianna, instructor of internal medicine; and Dr. Joel Elmquist, professor of internal medicine and director of the Center for Hypothalamic Research at UT Southwestern.
The study was supported by the American Heart Association, National Institutes of Health and the American Diabetes Association.

A latest medical study have shown that air pollution could lead to appendicitis.
The research, made by researchers at the University of Calgary, University of Toronto and Health Canada, looked at 5191 adults admitted to hospital in Calgary, Alberta, Canada. Fifty-two per cent of admissions occurred between April and September, the warmest months of the year in Canada during which people are more likely to be outside.
The dominant theory of the cause of appendicitis has been obstruction of the appendix opening, but this theory does not explain the trends of appendicitis in developed and developing countries. Appendicitis cases increased dramatically in industrialized countries in the 19th and early 20th centuries, then decreased in the middle and late 20th century, coinciding with legislation to improve air quality. The incidence of appendicitis has been growing in developing countries as they become more industrialized.
Using Environment Canada’s air pollution data for Calgary, the researchers determined the levels of ozone, nitrogen dioxide and other air-borne pollutants along with temperature.

The public needs to be careful since new pieces of evidence have shown that air pollution could lead to appendicitis.

They found correlations between high levels of ozone and nitrogen dioxide and the incidence of appendicitis between age groups and genders. More men than women were found to have the condition.
"For unexplained reasons, men are more likely than women to have appendicitis," write Dr. Gilaad Kaplan of the University of Calgary and coauthors. "Men may be more susceptible to the effects of outdoor air pollution because they are more likely to be employed in outdoor occupations," although they note that misclassifications of data could explain some of the difference.
While it is not known how air pollution may increase the risk of appendicitis, the authors suggest pollutants may trigger inflammatory responses. They recommend further studies to determine the link.

A leading medical organization has warned parents around the world warned parents to be careful with the disease dubbed as acid reflux since it can cause death if not given proper and immediate treatment.
The medical name for the disease is gastroesophageal reflux. It means stomach + esophagus + backwash.
The Pediatric Adolescent Gastroesophageal Reflux (PAGER) Association has been helping families learn about acid reflux since 1992.
Beth Pulsifer-Anderson, Director of PAGER Association revealed acid reflux in children is often overlooked.
Based on medical facts some of the clues of the disease include excessive crying, ‘colic’, a burning sensation in the throat or chest, tummy aches, spitting up, a sensation of
food coming up, poor appetite, poor weight gain, trouble swallowing, night waking, ear infections, sinus problems, asthma, wheezing, tooth decay and bad breath.
Pulsifer-Anderson added untreated reflux can cause excruciating pain and serious health problems.
She explained a child with acid reflux is often miserable and this affects the whole family.
Moreover said she said PAGER Association has been contacted by more and more Spanish speaking families in recent years.
According to studies, about 6 million Hispanics in the US have acid reflux symptoms and most don’t seek treatment.
Pulsifer-Anderson says, "It is important for Spanish speaking parents to know about acid reflux so they can be sure their children can get appropriate medical attention.

 

Parents worldwide need to be careful about acid reflux since it can lead to the death of their children.

A medical expert said there is a big possibility that the treatment for tuberculosis could be shortened for patients.

To offer relief to patients suffering from tuberculosis an intensive research is currently been undertaken to shorten the usual long treatment for the deadly lung disease.
Based on the medical study conducted by Dutch researcher Hanneke Later-Nijland, it may be possible to shorten the duration of treatment for tuberculosis.
It is said that due to the long duration of treatment, not every patient sees it through.
Partly because of this, tuberculosis is one of the most lethal diseases in developing countries.
The research conducted by Hanneke Later-Nijland is helping to shorten the duration of treatment for tuberculosis.
Later-Nijland studied different groups of Indonesian tuberculosis patients. She believes it may be possible to shorten the duration of treatment by increasing the dose of the important drug rifampicin. After increasing the dose, the concentration of the drug in the blood plasma was higher than expected.
In addition, the tuberculosis patients in Later-Nijland’s study did not experience more or different adverse effects at an increased dose than at a standard dose. Therefore increasing the dose of rifampicin might make it possible to reduce the length of treatment for tuberculosis without additional consequences. Research involving larger groups of patients will be needed to confirm this conclusion.

Tuberculosis and diabetes
 

Later-Nijland also conducted research into the reduced effectiveness of treatment in tuberculosis patients who also have type 2 diabetes. Her research revealed that the concentration of rifampicin in the blood plasma of patients with type 2 diabetes was lower than in patients with tuberculosis alone but who were administered the same dose. Whether tuberculosis patients with type 2 diabetes would benefit from a higher dose of rifampicin is a subject for further research.
Hanneke Later-Nijland started her research in October 2004 at Radboud University Nijmegen Medical Centre. She carried out her research within the Indonesian, Tanzanian and Dutch research network Poverty Related Infection Oriented Research, or PRIOR. PRIOR focused on research into poverty-related infectious diseases such as tuberculosis, HIV and malaria, and was funded by NWO.

According to a latest research it was discovered that pain in elderly with dementia are often undetected.
The researchers discovered that the elderly who suffer from dementia aren’t able to say when something hurts or is sore.
They may demonstrate their pain through behaviours like rocking or striking out, and we often dismiss these actions as symptoms of the dementia instead of pain, which is usually from a different problem.
The researchers revealed arthritis, diabetic neuropathy, fractures, muscular contractures, bruises, abdominal pain and mouth ulcers are among the list of common ailments that go undetected.

The family of elderly suffering from dementia need to be vigilant since studies show the pain suffered by these people often goes undetected.

The research team explained it is important for those who live or work with persons with dementia to know how to identify when an elderly person is experiencing pain and receive treatment sooner rather than later.
The University of Alberta’s Cary Brown, PhD, has a new tool to help.
She has developed an on-line workshop and toolkit for caregivers, health-care providers, family members and friends of people with dementia.
The researcher from the Faculty of Rehabilitation Medicine created an evidence-based website with a narrated presentation on pain and dementia, a downloadable resource pack for family members, a downloadable pain log and a facilitator’s toolkit with background material, a planning guide, promotional material and supplemental information for organizations who wish to put on a workshop.