Therapist Unlimited Blog

According to a latest medical study a great number of childhood cancer survivors are afraid to marry when they reach adulthood due to the long-term effects of cancer treatment on physical health.
Based on the research conducted by the  Yale School of Medicine, Yale Cancer Center, and Health Education, Research & Outcomes for Survivors (HEROS) Clinic for childhood cancer survivors it was discovered that e 20 to 25 percent of cancer survivors are more likely "to never marry" compared with siblings and the general population.
Lead researcher Nina S. Kadan-Lottick, M.D., M.S.P.H., assistant professor at Yale School of Medicine and Yale Cancer Center, and medical director of the Health Education, Research & Outcomes for Survivors (HEROS) Clinic for childhood cancer survivors explained many childhood cancer survivors still struggle to fully participate in our society because of the lasting cognitive and physical effects of their past cancer therapy.
Using data from the Childhood Cancer Survivor Study, a retrospective cohort of more than 10,000 childhood cancer survivors (who are now adults) treated at 26 institutions around the country, Kadan-Lottick and colleagues evaluated the frequency of marriage and divorce rates among survivors compared with their sibling group and U.S. Census data. The Childhood Cancer Survivor Study is an ongoing study funded by the National Cancer Institute.

Childhood cancer survivors should not be afraid to get married since marriage is part of life.
 

Researchers distributed surveys to participants to determine late outcomes of therapy, medical problems, subsequent cancers, psychosocial functioning and other aspects of survivorship, according to the researchers. They identified patients and treatment factors that may predict marital status, including psychosocial distress and neurocognitive impairment.
"Our study pinpointed what aspects of the survivor experience likely contribute to altered marriage patterns: short stature, poor physical functioning and cognitive problems," said Kadan-Lottick. "These conditions are known to be associated with certain chemotherapy and radiation exposures."
Results showed that an estimated 42 percent of survivors were married, 7.3 percent were separated or divorced and 46 percent were never married.
Those who survived brain tumors were 50 percent more likely never to marry. Survivors of central nervous system tumors and leukemia had the greatest likelihood of never marrying, according to the study. Cranial radiation was the therapy most associated with not getting married.
Likelihood of divorce did not vary between the study populations.
"While it can be debated whether marriage is a desirable outcome, marriage is generally an expected developmental goal in our society to the extent that most U.S. adults are married by the age of 30. Our results suggest that survivors of childhood cancer need ongoing support even as they enter adulthood," Kadan-Lottick suggested.
Electra D. Paskett, Ph.D., who was not involved with the study, but is a deputy editor of Cancer Epidemiology, Biomarkers & Prevention, said these findings shed light on the use of certain treatments and their long-term implications, which may affect a patient’s physical appearance, thereby resulting in social effects.
"In other studies marital status has been found to be a significant predictor of survival. Will we see this among the childhood survivors as well?" asked Paskett, who is the Marion N. Rowley professor of cancer research in the Division of Epidemiology, and associate director for population sciences in The Ohio State University Comprehensive Cancer Center.
As a follow-up to this report, separate analyses are underway to better understand factors that contribute to other adult benchmarks among childhood cancer survivors, such as living independently, achieving higher education and income.

Medical researchers has recently discovered that walking is beneficial to breast cancer survivors since it reduces chances of the recurrence of the deadly disease by 40 percent.
Dr. Carolyn Kaelin, a Harvard surgeon, breast cancer survivor and author of The Breast Cancer Survivor’s Fitness Plan, explained brisk walking about 3.0 mph on a treadmill
for three to five hours per week, or about 30 minutes a day, can net big benefits for breast cancer survivors.
With the huge rewards it offers to breast cancer survivors Kaelin, in conjunction with The Breast Cancer Research Foundation (BCRF) and CYBEX exercise equipment, is promoting brisk walking and the benefits of cardio exercise through CYBEX Pink Ribbon Run for Breast Cancer Awareness Month, this October.
Based on the study made by the the Nurses Health Study published in the Journal of American Medical Association (JAMA) nearly 3,000 women up to 14 years after their breast cancer diagnosis and found that cardiovascular and aerobic physical activities
reduced the likelihood of breast cancer recurrence and increased the odds of living longer.
Kaelin revealed recurrence rates and deaths from breast cancer decreased by 40 percent among those who exercise at least 3-5 hours per week, compared with those who were sedentary.

To avoid chances of having breast cancer again, breast cancer survivors should do some walking in a regular basis.
 

She added it does not need to be running a marathon, or biking a century, but rather simply walking briskly most days on a treadmill, at a shopping mall or around a track, that further reduces breast cancer recurrence for those who have been treated for the condition.
She added to all women, in addition to physical activity helping to optimize body weight and reduce high blood pressure, heart disease and diabetes, scientific research is more strongly pointing to the positive effects of cardio-vascular exercise in reducing breast cancer risk and the risks of other forms of cancer, too.
 

Those women, who survived cancer during their childhood, need to closely monitored since recent medical studies has shown that they are at higher risk of birth complications.
Dr. Sharon Lie Fong, of the Department of Obstetrics and Gynaecology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands and her colleagues get the data after studying the pregnancies of 40 women who had been treated for cancer during their childhood, the majority of them for leukaemia, but also for solid tumours.
Fong said from their subjects, six had had radiation treatment directly to the abdomen.
She said the data they gathered were compared with those from a control group of more than 9,000 women who had not had cancer treatment.
She added all data were obtained from The Netherlands Prenatal Register, a nationwide database of pregnancy outcomes.
The medical expert said data were matched for age at pregnancy, year and month of delivery, and the number of times the woman had given birth.
The medical expert added the team did not investigate overall fertility and miscarriage rates, but they believe that it is possible that the fertility of all the cancer survivors will be compromised.
Fong said the ovarian reserve or capacity of the ovary to provide eggs capable of fertilisation, is established in the foetus and decreases during a woman’s reproductive lifetime.

Women who survived cancer during their childhood need to be careful since they are at higher risk of birth complications.

Fong added women with a poor ovarian reserve are less likely to conceive, even with assisted reproduction therapies, than those with a normal number of eggs.
She said women might also have an earlier menopause, as their stock of eggs is exhausted at a younger age.
She revealed long-term, multi-disciplinary follow-up for female child cancer survivors is mandatory.
Furthermore, the researchers said although at the start of treatment, future fertility may not be of great concern to care providers; it is to the patient’s parents.
The researchers added during follow-up, survivors should be made aware of the possible late effects of their treatment.
They said in addition to the deleterious effects of abdominal radiotherapy on reproductive function, radiotherapy to the head can also cause problems by causing the hypothalamus to reduce the production of follicle stimulating hormone and luteinizing hormone, both important in promoting ovulation.
The team believe that it is particularly important for all female children who are treated for cancer, and their parents, to be made aware of this risk.
They said their research has also shown how important it is that, if they do become pregnant, childhood cancer survivors should be closely monitored throughout their pregnancy and that they are delivered in a clinical setting, rather than at home.
The researchers concluded that even if at first fertility seems normal for childhood cancer survivors, there may be problems later in life.